Cligel-A Gel is a topical acne treatment that combines Adapalene (0.1%) and Clindamycin (1%)

It works by normalizing skin cell turnover (reducing clogged pores) and killing acne-causing bacteria to reduce inflammation and prevent new breakouts such as pimples, blackheads, and whiteheads.

Common side effects include mild skin irritation, dryness, burning, or peeling, especially in early use. It's for external use only and should be applied as a thin layer on clean, dry skin, usually once daily at night.

Composition & Basic Facts

• Active Ingredients:
  • Adapalene 0.1% (w/w)
  • Clindamycin 1% (w/w)
• Form / Strength: Topical gel, e.g. 15 g tube.
• Manufacturer: East West Pharma (India)
• Therapeutic Class: Anti-acne / dermatological combination (retinoid + antibiotic)

Mechanism of Action

Cligel-A Gel combines two complementary modes of action to treat acne:

1. Adapalene (a retinoid)

• Promotes normalization of skin cell turnover (prevents dead cells from blocking follicles)
• Helps prevent comedones (blackheads/whiteheads)
• Exerts anti-inflammatory effects, reducing redness and swelling

2. Clindamycin (a topical antibiotic)

• Inhibits bacterial protein synthesis, suppressing growth of Propionibacterium acnes and other acne-causing bacteria in follicles
• Reduces bacterial load and thereby helps reduce inflammation and infection risk in acne lesions

By combining these two, the product addresses both clogged pores / abnormal cell turnover and the bacterial / inflammatory component of acne.

Indications / Uses

Cligel-A Gel is used for:

• Acne vulgaris (mild to moderate) — on face, chest, back.
• Reducing comedones (blackheads, whiteheads), papules, pustules.
• Improving overall skin appearance by reducing oiliness, inflammation, and lesions.

Dosage & Application / Instructions

• Typically once daily, preferably in the evening / before bedtime.
• Before applying, cleanse the affected area gently and pat dry.
• Use a thin film (small amount) over affected skin. Avoid overuse — more is not better.
• Avoid application on broken, irritated, sunburned, or eczematous skin.
• Avoid contact with eyes, lips, nostrils; if accidental contact, rinse thoroughly with water.
• Wash hands before and after application (if hands are not part of the treated area).